Aplication of Peptide in Veterinary Technology and Animal Production

Eni Kusumaningtyas

Abstract

Peptide to improve human and livestock health status present as natural or artificially manufactured compound.  In veterinary and livestock production, antimicrobial peptides used to combat bacterial infection especially for antibiotic resistant bacteria and to preserve semen in artificial insemination. In vaccine technology, peptide can be applied to replace conventional vaccine especially for very highly contagious virus such foot and mouth disease virus (FMDV). Other peptides were used as a diagnostic tool such as  ELISA to detect antibodies against H5N1 avian influenza virus, C- peptide to diagnose diabetic animals, and a synthetic peptide caerulein to detect pancreatic dysfunction. Some synthetic peptides are used in veterinary medicine and livestock breeding such as GnRH, desiorelin, leuprolide and buserelin. Natural peptides are also used as medicine. Peptide-based drugs are metabolized more readily than other small molecules, that means less risk of contamination in animal products such as eggs or meat. A fibrin adhesive (seal) peptide which developed from animal venom has been successfully applied in the surgery and as good alternative to conventional sutures. Other peptide from cobra venom was developed as an analgesic which has greater activity than morphine without causing drug addiction. This paper describes the application of peptide in detail and possible utilization in Indonesia.

Keywords

Application; peptide; veterinary; animal production

References

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