Plasma Β-Endorphin and Cortisol Profiles around Periparturient Period at Stressful Conditions in Egyptian Buffalo

Ha El-Hady Abed, O M El-Malky, Reem S Mourad, I S Al-Gezery

Abstract

The study determined the level of plasma β-endorphin and cortisol concentrations in peripheral blood circulation of buffalo cows suffering from reproductive disorders (dystocia and retained placenta) and weakness body condition score during periparturient period. Twenty multi-parous Egyptian buffalo cows at late pregnancy period were used for two months before parturition. β-endorphin concentrations were higher in buffalo suffering from reproductive disorders groups. Whereas, β-endorphin concentrations were 134.9±4.8 for retained placenta, 121.3±4.9 for dystocia, 114.2±8.4 for weakness and 113.5±6.5 pg/ml for control. In the closer period around parturition both of plasma β-endorphin and cortisol followed the same trend toward a gradually increased values during -2,-1days and zero time in all groups. A concomitant trend was noticed in β-endorphin and cortisol concentrations in postpartum period with reduce values were observed in all groups after parturition continued for month or more. Buffalo suffering from reproductive disorders were showed a high relative values in β-endorphin and cortisol concentrations. A significant differences (P<0.01) were observed between the experimental groups. Generally, buffaloes suffering reproductive disorders had a clear impact on blood plasma β-endorphin concentration around parturition process.

The aim of this study was to determine the relationship between various reproductive disorders as a stress factors with plasma β–endorphin and cortisol in buffalo cows around parturition and changes in these parameters could be used as an objective measure of the stress associated labour. Stress has been hypothesized to be a cause of impaired reproductive efficiency. Stress may cause an overproduction of beta-endorphins and free radicals

Keywords

Buffalo, β-endorphin, cortisol, dystocia, retained placenta

References

Akar Y. & Gazioglu A. (2006) Relationship between vitamin A and beta-carotene levels during the postpartum period and fertility parameters in cows with and without retained placenta. BULLETIN-VETERINARY INSTITUTE IN PULAWY 50, 93.

APRI, (1997): Animals Production Research Institute, Ministry of Agriculture. Animal and Poultry Nutrition (In Arabic), Giza, Egypt.

Aurich J., Dobrinski I., Hoppen H.-O. & Grunert E. (1990) β-Endorphin and met-enkephalin in plasma of cattle during pregnancy, parturition and the neonatal period. Reproduction 89, 605-12.

Aurich J., Dobrinski I., Hoppen H. & Grunert E. (1993) Stimulation of release of β-endorphin and oxytocin by prostaglandin F2α in cattle at parturition. Reproduction 97, 161-6.

Bruckmaier R. & Wellnitz O. (2008) Induction of milk ejection and milk removal in different production systems. Journal of animal science 86, 15-20.

Bruckmaier R.M., Schams D. & Blum J.W. (1993) Milk removal in familiar and unfamiliar surroundings: concentrations of oxytocin, prolactin, cortisol and β–endorphin. Journal of Dairy Research 60, 449-56.

El-Azab M., Whitmore H., Kakoma I., Brodie B., McKenna D. & Gustafsson B. (1988) Evaluation of the uterine environment in experimental and spontaneous bovine metritis. Theriogenology 29, 1327-34.

Ettema J. & Santos J. (2004) Impact of age at calving on lactation, reproduction, health, and income in first-parity Holsteins on commercial farms. Journal of Dairy Science 87, 2730-42.

Evans P., Dieguez C., Rees L., Hall R. & Scanlon M. (1986) The effect of cholinergic blockade on the ACTH, β‐endorphin and cortisol responses to insulin‐induced hypoglycaemia. Clinical endocrinology 24, 687-91.

Fordham D., Al-Gahtani S., Durotoye L. & Rodway R. (1991) Changes in plasma cortisol and β-endorphin concentrations and behaviour in sheep subjected to a change of environment. Animal Science 52, 287-96.

Hamada H., Kishioka S., Yamoto M. & Nakano R. (1995) [3 H] Naloxone binding sites in porcine ovarian follicles and corpora lutea during the ovarian cycle. European journal of endocrinology 132, 622-6.

Heuwieser W., Hartig U., Offeney F. & Grunert E. (1987) Significance of glucocorticoids as a parameter of stress in cattle in the periparturient period. Journal of Veterinary Medicine, Series A (Germany, FR).

Hoyer C., Grunert E. & Jöchle W. (1990) Plasma glucocorticoid concentrations in calves as an indicator of stress during parturition. American journal of veterinary research 51, 1882-4.

Hydbring E., Madej A., MacDonald E., Drugge-Boholm G., Berglund B. & Olsson K. (1999) Hormonal changes during parturition in heifers and goats are related to the phases and severity of labour. Journal of Endocrinology 160, 75-86.

Kaminski T., Siawrys G., Bogacka I. & Przala J. (2000) The physiological role of $beta $-endorphin in porcine ovarian follicles. Reproduction Nutrition Development 40, 63-75.

Kindahl H., Kornmatitsuk B., Königsson K. & Gustafsson H. (2002) Endocrine changes in late bovine pregnancy with special emphasis on fetal well-being. Domestic animal endocrinology 23, 321-8.

Lacasse P. & Ollier S. (2014) Effect of premilking stimulation and milking frequency on milking-induced prolactin release in lactating dairy cows. Domestic animal endocrinology 47, 47-54.

Mohammad D.R.I. & Abdel-Rahman M.A.M. (2013) A comparative study on behavioral, physiological, and adrenal changes in buffaloes during the first stage of labor with normal and difficult parturition. Journal of Veterinary Behavior: Clinical Applications and Research 8, 46-50.

Mourad R.S. (2017) Plasma chemical composition and progesterone hormone on day of estrus in Egyptian buffalo cows. Buffalo Bulletin 36, 629-37.

Nakao T. & Grunert E. (1990) Effects of dystocia on postpartum adrenocortical function in dairy cows. Journal of Dairy Science 73, 2801-6.

Nakao T., Tamamura F., Tsunoda N. & Kawata K. (1981) Double antibody enzyme immunoassay of cortisol in bovine plasma. Steroids 38, 111-20.

O’Driscoll K., Olmos G., Moya S.L., Mee J., Earley B., Gleeson D., O’Brien B. & Boyle L. (2012) A reduction in milking frequency and feed allowance improves dairy cow immune status. Journal of Dairy Science 95, 1177-87.

Osawa T., Nakao T., Moriyoshi M. & Nakada K. (1998) Plasma β-endorphin around parturition and its relationship to cortisol level and resumption of pituitary and ovarian functions in dairy cows. Animal Reproduction Science 52, 27-38.

Osawa T., Nakao T., Moriyoshi M. & Nakada K. (2000) Effects of dystocia, retained placenta and body condition on plasma β-endorphin profile in periparturient dairy cows. Journal of Reproduction and Development 46, 23-30.

Ribeiro E., Lima F., Greco L., Bisinotto R., Monteiro A., Favoreto M., Ayres H., Marsola R., Martinez N. & Thatcher W. (2013) Prevalence of periparturient diseases and effects on fertility of seasonally calving grazing dairy cows supplemented with concentrates. Journal of Dairy Science 96, 5682-97.

Sathya A., Prabhakar S. & Ghuman S. (2005) Effect of dexamethasone administration on cortisol concentration and biochemical profile in buffaloes suffering from dystocia. Anim. Reprod 2, 233-9.

SAS (2003). SAS user's guide ver.9.1: Statistics. SAS Inst. Inc. Cary NC.

Scott S., Schaefer A., Jones S., Mears G. & Stanley R. (1993) Stress indicators and lean tissue yield in transported cattle treated with electrolyte. In: Proceedings of the 39th International Congress of Meat Science and Technology, Calgary, Alberta, Canada, p. 22.

Sepúlveda-Varas P., Huzzey J., Weary D. & Von Keyserlingk M. (2013) Behaviour, illness and management during the periparturient period in dairy cows. Animal production science 53, 988-99.

Shutt D., Smith A., Wallace C., Connell R. & Fell L. (1988) Effect of Myiasis and Acute Restraint Stress on Plasma Levels of Immunoreactive, ß-Endorphin, Adrenocorticotrophin (ACTH) and Cortisol in the Sheep. Australian journal of biological sciences 41, 297-302.

Sordillo L.M., Contreras G. & Aitken S.L. (2009) Metabolic factors affecting the inflammatory response of periparturient dairy cows. Animal health research reviews 10, 53-63.

Sutherland M. & Huddart F. (2012) The effect of training first-lactation heifers to the milking parlor on the behavioral reactivity to humans and the physiological and behavioral responses to milking and productivity. Journal of Dairy Science 95, 6983-93.

Tančin V., Kraetzl W., Schams D., Mihina Š. & Hetényi L. (2000) The oxytocin secretion and milk letdown during milking immediately after the change of milking and housing conditions. Veterinarni Medicina 45, 1-4.

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